Are metabotypes the next big thing in personalised nutrition?
Personalized Nutrition Update issue nr. 27/20
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Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement
This study measured the plasma levels of a gut leakage marker (LPS-binding protein, LBP), a marker of enterocyte damage (intestinal fatty acid binding protein, IFABP), a gut homing marker (CCL25, ligand for chemokine receptor CCR9) and markers of inflammasome activation (IL-1β, IL-18 and their regulatory proteins). It aimed to relate them to the cardiac involvement in 39 COVID-19 patients. The results showed that “compared to controls, COVID-19 patients had elevated plasma levels of LBP and CCL25 but not IFABP, suggesting impaired gut barrier function and accentuated gut homing of T cells without excessive enterocyte damage (…) Also, markers of inflammasome activation were moderately elevated in patients with cardiac involvement. LBP was associated with higher NT-pro-BNP levels, whereas IL-18, IL-18BP and IL-1Ra were associated with higher troponin levels”.
This review aimed to analyze “a unique data set on packaged food products in the United States across 44 categories over 16 years”. The results showed that “FOP (front-of-package nutrition labeling) system adoption in a product category leads to an improvement in the nutritional quality of other products in that category. This competitive response is stronger for premium brands and brands with narrower product line breadth as well as for categories involving unhealthy products and those that are more competitive in nature”
This study aimed to optimise a metabotype approach to deliver targeted dietary advice by encompassing more specific recommendations on nutrient and food intakes and dietary behaviours. The optimised metabotype approach proved capable of delivering targeted dietary advice for healthy adults, being highly comparable with individualised advice
This study determined whether age, sex and/or race/ethnicity moderate associations of lifestyle/behavioural factors with relative telomere length (RTL). Findings nclude novel variations by sex and race/ethnicity in associations between lifestyle/behavioural factors and RTL
This study aimed to identify a compact set of fecal microbial biomarkers of food intake with high predictive accuracy. Blood and fecal bacteria were measured in 285 healthy participants following a controlled diet. Findings concluded that food consumption by healthy adults can be predicted using fecal bacteria as biomarkers. The fecal microbiota may provide useful fidelity measures to ascertain nutrition study compliance.
Cracking the clean label conundrum: Beneo discusses tapping consumer desire for fewer ingredients and improved nutritional profiles
– In 2030, older adults will want to eat food that has other flavors and ingredients that are influenced by their experiences of other food cultures. Their preferences for traditional and familiar dishes will not align with alternative ways to consume nutrients such as pills or injections.
– Sustainability will be very important because now many are vegans or vegetarians and alternative sources for meat have become normal. On the other hand, new protein sources such as insects, 3-D printed meat, cell-grown meat, and plant protein, will have increased their market share among younger adults but will not have established themselves in the everyday food of the oldest adults in 2030.
– Eating “on the go” will not be an option, and lunch will be the meal that the majority eats out as well as the most social meal.
– By 2030, physical meetings and digital meetings places will be alternated.
– Ten years from now, the researchers expect that older people will continue to pay for groceries at supermarkets and local food stores.